产品货号：
Z32903
中文名称：
CD146/MCAM抗体
英文名称：
Anti-CD146/MCAM Antibody (Clone#4C12)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CD146/MCAM Antibody (Clone#4C12) |
| 指标别名 | CD146;MCAM;MUC18 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IHC-F,FCM |
| 基因名称 | MCAM |
| 克隆号 | 4C12 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | E.coli-derived human CD146 recombinant protein (Position:H59-A401).Human CD146 shares 73% amino acid (aa) sequence identity with both mouse and rat CD146. |
| 实际分子量 | 100KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | CD146 (cluster of differentiation 146),also known as the melanoma cell adhesion molecule (MCAM) or cell surface glycoprotein MUC18,is a 113kDa cell adhesion molecule currently used as a marker for endothelial cell lineage.MCAM,a member of the immunoglobulin superfamily,is homologous to several cell adhesion molecules and is associated with tumor progression and the development of metastasis in human malignant melanoma.By radiation hybrid analysis,this gene is mapped to chromosome 11q23.3.MCAM has been demonstrated to appear on a small subset of T and B lymphocytes in the peripheral blood of healthy individuals.MCAM has been seen as a marker for mesenchymal stem cells isolated from multiple adult and fetal organs,and its expression may be linked to multipotency mesenchymal stem cells with greater differentiation potential express higher levels of MCAM on the cell surface. |
| Uniprot ID | P43121 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | melanoma cell adhesion molecule |
| 蛋白名全称 | Cell surface glycoprotein MUC18 |
| 推荐稀释比 | Flow cytometry (FCM) 1～3μg/1×106 cells Western blot(WB) 1:500～2000 mmunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 29 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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